Real-Time Reaction Monitoring in the Chemical Industry

This collection of webinars focuses on applications for real-time reaction monitoring in the chemical industry, illustrated by practical examples and case studies demonstrating various techniques in practice. Topics include in situ spectroscopy, and size distribution measurement and imaging for particles, droplets and bubbles.

Real-time reaction monitoring is important in the chemical industry, helping to ensure process control for exothermic reactions and maintain safety in the laboratory, as well as being a valuable tool to accelerate process research and development. This popular series of on-demand webinars, already viewed by hundreds of researchers, follows experts in the field as they discuss different approaches to in situ reaction monitoring, their benefits, and how these methods have been put into practice in the industry.


Monitor Reactions In Situ in the Chemical Industry: IR, Raman, NIR – Which One to Use?

This webinar discusses the pros and cons of a range of in situ monitoring techniques, with a particular focus on in situ spectroscopy for process research and development. It uses a selection of case studies to demonstrate the advantages of these techniques, including real-time process information, tracking of labile transient intermediates, and fully automated data collection and analysis. It also provides examples of how in situ spectroscopy can help to accelerate process research through:

• monitoring of multi-step synthesis for complex organic molecules
• monitoring two-phase silicone polyether reactions
• simultaneous monitoring of silsesquioxane by IR, Raman, NIR and NMR.

Moderator: Shawn Chen, PhD, Dow Chemical Company
Duration: 34 minutes
Language: English

Shawn Chen is an innovative analytical chemist with expertise in, and a passion for, optical spectroscopy. He has over 10 years of industrial experience in spectroscopic and chemometric method development for R&D, mini-plant and manufacturing plant projects, and five years of academic experience in method development for nonlinear optical spectroscopy. Shawn currently heads Dow's world-class optical spectroscopy group, and is a subject matter expert in infrared, Raman, and near-infrared spectroscopy.


Using ParticleTrack and ParticleView for Lubricant Technology Applications

This presentation reviews the use of probe-based technologies for real-time size distribution measurement and imaging of particles, droplets and bubbles in real concentrations. It covers:
• use of particle size analyzers for insoluble size distribution measurement and visualization in engine drain oils, to understand the oil dispersancy
• antifoam polymer droplet characterization in gear oil samples, using size distribution and visualization to understand incorporation efficiency
• characterization of air bubbles trapped in oil after aeration, using bubble dissipation rate and visualization

Anil Agiral is a senior research engineer at the Formulation Science Division of Lubrizol Corporation in Cleveland, Ohio. He focuses on the application of colloid and interfacial science to support the development of robust products, generate fundamental knowledge regarding component interactions, and develop new capabilities/methods for product development and differentiation. Previously, he was a research scientist at Chevron Corporation, as well as Lawrence Berkeley National Laboratory. He has a PhD from the University of Twente in the Netherlands.


Process Development of Organosilicon Flame Retardants

Chemical engineers and chemists working in the pharmaceutical and chemical industries, as well as in related academic fields, will benefit from this webinar discussing the process development of organosilicon flame retardants, including practical examples and case studies.

The production of organosilicon flame retardants requires careful control of an exothermic reaction to ensure process safety. This presentation describes how this was achieved using in situ Fourier-transform infrared (FTIR) spectroscopy and reaction calorimetry during the development of a new silicon-based, halogen-free flame retardant. In situ FTIR spectroscopy enabled a better understanding of the effect of different parameters on the reaction rate and chemical structure. The ability to monitor the reaction in real time helped to avoid the accumulation of energetic reactants, reducing the risk of a runaway reaction. Reaction calorimetry was used to gather additional information, including the heat of reaction, temperature effects and initiation behaviour. The use of these advanced process analysis tools allowed a large amount of data to be collected with just a few carefully planned experiments, enabling a safe, scalable process to be developed.

Moderators: Mike DePierro, John Gohndrone, Brian Deeth, Dow Corning Corporation
Duration: 31 minutes
Language: English

Mike DePierro works in the Process R&D group within the Dow Performance Silicones business. He has been involved with several organosilane process development projects since joining Dow Corning. He leads the Process Chemistry Community of Practice for the Dow Performance Silicones business, and recently led the Specialty Siloxanes Tech Center program, contributing to the expansion of the organosiloxane product range. Prior to joining Dow Corning, he was employed with General Electric and Sabic Innovative Plastics, with different roles in process and product development. He completed a PhD in Chemical Engineering at the University of Iowa.

John Gohndrone is a Process Research and Development Fellow with the Dow Chemical Company. He has 31 years of experience focused on the development, scale-up, implementation and improvement of process technology for organofunctional silanes and silicones. During the past 20 years, he has been involved in the development of a number of phase-transfer-catalysis (PTC) processes for the production of organofunctional silanes, and has seven patents and publications related to PTC process technology. Before joining the Dow Chemical Company, he worked for Dow Corning Corporation, having joined in 1987. He received a BS degree in chemical engineering from the Illinois Institute of Technology, and an MS and PhD in Chemical Engineering from the University of Illinois at Champaign-Urbana.

Brian Deeth is currently a Senior Process Research and Development Scientist with the Dow Chemical Company. He has over 30 years’ industrial experience, with over 20 years in Process R&D for silicone organic hybrid materials. His professional background also includes analytical chemistry and evaluation of reactive chemical hazards. Prior to joining the Dow Chemical Company in 2016, he was employed by Dow Corning Corporation. He earned a BS in Chemistry from University of Wisconsin at La Crosse.